Exploration of Immunology

Table 3. The area under the ROC curve for all tested antibodies

Method of determination	aPL	AUC	P	95% CI
ELISA	IgG aCL	0.737	0.005	0.583–0.891
	IgM aCL	0.582	0.336	0.405–0.758
	IgG anti-β₂-GPI	0.737	0.005	0.587–0.887
	IgM anti-β₂-GPI	0.557	0.501	0.390–0.724
	IgG aPS/PT	0.748	0.003	0.596–0.901
	IgM aPS/PT	0.555	0.519	0.369–0.740
CLA	IgG aCL	0.767	0.002	0.607–0.927
	IgM aCL	0.578	0.377	0.400–0.755
	IgA aCL	0.714	0.015	0.535–0.894
	IgG anti-β₂-GPI	0.752	0.004	0.583–0.922
	IgM anti-β₂-GPI	0.557	0.383	0.398–0.756
	IgA anti-β₂-GPI	0.674	0.049	0.492–0.856
	IgG anti-β₂-GPIDI	0.717	0.014	0.549–0.885

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P value ≤ 0.05 represents significance difference

Declarations

Acknowledgments

The study conducted within the framework of fundamental research project FURS-2022-003 [1021051402790].

Author contributions

FAC: Conceptualization, Validation, Writing—original draft, Writing—review & editing, Project administration. AAS: Writing—original draft, Writing—review & editing, Project administration. MVC and SIG: Validation. AML: Project administration. ELN: Project administration, Supervision. TMR: Methodology, Writing—original draft, Writing—review & editing, Project administration, Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

The study was conducted in accordance with the Declaration of Helsinki, and approved by Ethics Committee of V.A. Nasonova Research Institute of Rheumatology (Protocol No. 25 dated December 19, 2019).

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Informed consent to publication was obtained from relevant participants.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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