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Original Article
Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids
Aim:
The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-tri
Published: April 21, 2025 Explor Drug Sci. 2025;3:1008107
Open Access
Review
Natural products targeting cancer stem cells: a promising therapeutic approach
Cancer remains the second leading cause of death globally, posing an ongoing threat to public health. A hallmark of cancer cells is their capacity to invade adjacent tissues and evolve into malignan
Published: April 18, 2025 Explor Drug Sci. 2025;3:1008106
Open Access
Review
A narrative review on the role of gut microbiome, dietary strategies, and supplements in managing metabolic syndrome
Metabolic syndrome is a complex, multifactorial disorder, with emerging research emphasizing the significant role of gut health in its prevention and management. Recent studies suggest that dietary
Published: April 14, 2025 Explor Drug Sci. 2025;3:1008105
Open Access
Original Article
Revolutionizing diabetes treatment: computational insights into 4-hydroxy isoleucine derivatives and advanced molecular screening for antidiabetic compounds
Aim:
This study aimed to computationally identify and optimize 4-hydroxy isoleucine (4HILe) derivatives from fenugreek as multitarget antidiabetic agents against α-glucosidase, α-amylase, and a
Published: April 10, 2025 Explor Drug Sci. 2025;3:1008104
Open Access
Review
The use of peptides for deciphering the mechanism of EBV, HPV, and HCV invasion of human cells
Epstein-Barr virus (EBV), human papillomavirus (HPV), and hepatitis C virus (HCV) are significant human pathogens associated with various diseases, employing complex molecular mechanisms for cellula
Published: March 26, 2025 Explor Drug Sci. 2025;3:1008103
Open Access
Review
Novel progression on clinical therapy of COVID-19: Western and Traditional Chinese Medicines
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that causes a global epidemic named COVID-19. It still continues to plague humans with severe complications and un
Published: March 26, 2025 Explor Drug Sci. 2025;3:1008102
Open Access
Editorial
Drug discovery: a multifactorial ecosystem
Published: January 01, 2023 Explor Drug Sci. 2023;1:1–5
Open Access
Review
Approved antibacterial drugs in the last 10 years: from the bench to the clinic
Bacterial infections constitute one of the major cases of primary medical incidences worldwide. Historically, the fight against bacterial infections in humans has been an ongoing battle, due to the
Published: June 30, 2023 Explor Drug Sci. 2023;1:180–209
Open Access
Review
A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of
Published: August 28, 2024 Explor Drug Sci. 2024;2:484–507
Open Access
Review
Nature-inspired and medicinally relevant short peptides
Peptides constitute an important component of Nature’s pharmacy and they play a significant role in several signaling pathways acting as natural biological messengers. While nature has mastered th
Published: June 27, 2023 Explor Drug Sci. 2023;1:140–171
Open Access
Review
Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare
The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to drug production is crucial. This review focuse
Published: February 27, 2024 Explor Drug Sci. 2024;2:50–84
Open Access
Review
The protective role of GLP-1 in neuro-ophthalmology
Despite recent advancements in the field of neuro-ophthalmology, the rising rates of neurological and ophthalmological conditions, mismatches between supply and demand of clinicians, and an aging po
Published: August 28, 2023 Explor Drug Sci. 2023;1:221–238
Open Access
Review
Approved antibacterial drugs in the last 10 years: from the bench to the clinic
Bacterial infections constitute one of the major cases of primary medical incidences worldwide. Historically, the fight against bacterial infections in humans has been an ongoing battle, due to the
Published: June 30, 2023 Explor Drug Sci. 2023;1:180–209
Open Access
Review
Nature-inspired and medicinally relevant short peptides
Peptides constitute an important component of Nature’s pharmacy and they play a significant role in several signaling pathways acting as natural biological messengers. While nature has mastered th
Published: June 27, 2023 Explor Drug Sci. 2023;1:140–171
Open Access
Review
A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of
Published: August 28, 2024 Explor Drug Sci. 2024;2:484–507
Open Access
Review
Antioxidants from microalgae and their potential impact on human well-being
In recent times, there has been a revolutionary surge in antioxidant research, with a focus on harnessing microalgae to enhance wellness and extend human longevity. Microalgae, a diverse group of un
Published: May 31, 2024 Explor Drug Sci. 2024;2:292–321
Open Access
Review
The protective role of GLP-1 in neuro-ophthalmology
Despite recent advancements in the field of neuro-ophthalmology, the rising rates of neurological and ophthalmological conditions, mismatches between supply and demand of clinicians, and an aging po
Published: August 28, 2023 Explor Drug Sci. 2023;1:221–238
Open Access
Review
Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare
The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to drug production is crucial. This review focuse
Published: February 27, 2024 Explor Drug Sci. 2024;2:50–84
Open Access
Review
Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare
The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to drug production is crucial. This review focuse
Published: February 27, 2024 Explor Drug Sci. 2024;2:50–84
Open Access
Review
Antioxidants from microalgae and their potential impact on human well-being
In recent times, there has been a revolutionary surge in antioxidant research, with a focus on harnessing microalgae to enhance wellness and extend human longevity. Microalgae, a diverse group of un
Published: May 31, 2024 Explor Drug Sci. 2024;2:292–321
Open Access
Review
A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem
The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of
Published: August 28, 2024 Explor Drug Sci. 2024;2:484–507
Open Access
Review
Nature-inspired and medicinally relevant short peptides
Peptides constitute an important component of Nature’s pharmacy and they play a significant role in several signaling pathways acting as natural biological messengers. While nature has mastered th
Published: June 27, 2023 Explor Drug Sci. 2023;1:140–171
Open Access
Review
Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery
Seaweeds, also known as marine algae, have gained attention as a promising source of bioactive compounds with potential applications in drug discovery. This review explores the emerging field of sea
Published: December 28, 2023 Explor Drug Sci. 2023;1:475–496
Open Access
Review
The protective role of GLP-1 in neuro-ophthalmology
Despite recent advancements in the field of neuro-ophthalmology, the rising rates of neurological and ophthalmological conditions, mismatches between supply and demand of clinicians, and an aging po
Published: August 28, 2023 Explor Drug Sci. 2023;1:221–238
Special Issues
Ongoing Special lssues
Completed Special lssues
Essential Oils: Insights into Pharmacology, In Vivo, In Vitro and In Silico Studies
Prof. Mozaniel Santana de Oliveira
October 31, 2025
Published Articles: 0
Drug Repurposing: Accelerating Cancer Therapeutic Discoveries
Prof. Wei-Lin Jin Dr. Jin-Min Ma
August 31, 2025
Published Articles: 0
The Rise of Targeted Covalent Inhibitors in Drug Discovery
Prof. F. Javier Luque Prof. Jerônimo Lameira
September 30, 2025
Published Articles: 0
Bioactive Molecules from Natural Sources
Prof. Michio Kurosu
August 31, 2025
Published Articles: 1
Leveraging the FDA-Approved Kinase Inhibitors to Treat Neurological Disorders
Prof. Dazhi Liu
June 30, 2025
Published Articles: 2
Bioactive Peptides: Pioneering Innovations in Latin American Research
Fanny Guzmán Quimbayo Fernando Albericio
June 30, 2025
Published Articles: 9
Recent advances with investigational compounds and strategies to delay or reverse normal aging processes
Ricardo P. Garay, MD, PhD
June 30, 2025
Published Articles: 2
Discovery and development of new antibacterial compounds
Kamal Kumar
June 30, 2025
Published Articles: 3
Remedial benefits of natural products in inflammation and cancer
Noah Isakov Ruby John Anto
June 30, 2025
Published Articles: 6
Mimicking Nature: Biomimetics as Tools for Diagnosis and Therapeutics
Diego Núñez-Villanueva Rosario González-Muñiz
June 30, 2025
Published Articles: 3
Greening Drug Manufacturing for a Sustainable Healthcare
Prof. Alessandra Tolomelli Prof. Walter Cabri
June 30, 2025
Published Articles: 3
Innovative Therapeutics in Hepato-Gastroenterology
Prof. Amedeo Lonardo
June 30, 2025
Published Articles: 4
Preventive and Therapeutic Potential of Nutraceuticals in Non-communicable Diseases
Prof. Marcello Iriti
June 30, 2025
Published Articles: 2
Drug Discovery in Neuropsychiatric Diseases: therapeutic opportunities beyond the classic aminergic system
Prof. Santiago J. Ballaz Prof. Fernando Albericio
June 30, 2025
Published Articles: 0
Bioactive Peptides discovery and development
Prof. Xuechen Li
November 30, 2024
Published Articles: 10
Machine Learning for Drug Science
Prof. Walter Filgueira de Azevedo Jr.
May 31, 2025
Published Articles: 5
Emerging Nanomedicine Technologies for Enhanced Cancer Theranostics
Prof. Xiangyang Shi
April 30, 2025
Published Articles: 4
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