Spearman’s correlation matrix
| Parameter 1 | Parameter 2 | Spearman correlation (r) | Interpretation (Cohn’s criteria) | P-value |
|---|---|---|---|---|
| Monoclonal antibody | ||||
| HSA | Cholesterol total | –0.893 | Negative correlationHigh correlation | 0.012 (*) |
| HSA | HDL | –0.656 | Negative correlationHigh correlation | 0.110 |
| HSA | LDL | –0.750 | Negative correlationHigh correlation | 0.066 |
| Cholesterol total | HDL | 0.571 | Positive correlationHigh correlation | 0.200 |
| Cholesterol total | LDL | 0.857 | Positive correlationHigh correlation | 0.024 (*) |
| LDL | HDL | 0.786 | Positive correlationHigh correlation | 0.048 (*) |
| γGT | AP | 0.755 | Positive correlationHigh correlation | 0.001 (**) |
| Placebo | ||||
| HSA | Cholesterol total | –0.143 | Negative correlationWeak correlation | 0.783 |
| HSA | HDL | 0.619 | Positive correlationHigh correlation | 0.138 |
| HSA | LDL | 0.143 | Positive correlationWeak correlation | 0.783 |
| Cholesterol total | HDL | –0.214 | Negative correlationWeak correlation | 0.662 |
| Cholesterol total | LDL | 0.286 | Positive correlationWeak correlation | 0.556 |
| LDL | HDL | 0.429 | Positive correlationModerate correlation | 0.354 |
| γGT | AP | 0.192 | Positive correlationWeak correlation | 0.570 |
* Significant difference; ** highly significant difference. n: number of patients/events. γGT: gamma-glutamyltransferase; AP: alkaline phosphatase; HDL: high-density lipoprotein; HSA: human serum albumin; LDL: low-density lipoprotein