Model parameters, descriptions, and values are chosen for simulations
Notation | Value | Description |
---|---|---|
C | 7 × 10–1 | Cancer cells |
I | 2.1 × 10–2 | Immune system |
E | 3.8 × 10–1 | Elimination of cancer cells |
IC | 5.7 × 10–2 | Complex formed between the immune system and cancer cells |
c | 1 × 10–7 | Concentration of chemokines |
n | 3.42 × 10–10 | Concentration of immune cells |
k | 1.8 × 10–8 | Degradation rate of chemokines |
Dn | 1.3 × 10–4 | Diffusion coefficient of immune cells |
t | Est | Time |
χ | Est | Sensitivity of immune cells to chemokines |
D | 4.13 × 10–2 | Diffusion coefficient of chemokines |
cn | 5 × 10–3 | Sensitivity of concentration of chemokines |
Note. Adapted from “Modeling cancer immunoediting in tumor microenvironment with system characterizationthrough the ising-model Hamiltonian” by Rojas-Domínguez A, Arroyo-Duarte R, Rincón-Vieyra F, Alvarado-Mentado M. BMC Bioinformatics. 2022;30:200. (https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-022-04731-w#citeas). CC BY.