Differences in the serum concentrations of TRP-KYN pathway metabolites between HCs and PSOs
| Metabolites | HCs (mean ± SD) | PSOs (mean ± SD) | |
|---|---|---|---|
| TRP (μM) | 52.9 ± 7.26 | 48.0 ± 8.34 | |
| KYN (μM) | 2.00 ± 0.49 | 1.73 ± 0.47 | |
| KYNA (nM) | 37.6 ± 9.81 | 32.0 ± 16.8 | |
| AA (nM) | 17.1 ± 6.78 | 16.0 ± 12.2 | |
| 3HK (nM) | 18.8 ± 12.9 | 18.6 ± 8.76 | |
| 3HAA (nM) | 7.56 ± 4.52 | 14.2 ± 6.22 |
P < 0.05; **P < 0.01;***P < 0.001 vs. HCs