From:  Serum profiles of tryptophan-kynurenine pathway metabolites in psoriasis

Differences in the ratio of TRP-KYN pathway metabolites between HCs and PSOs

Ratios of metabolitesHCs (mean ± SD)PSOs (mean ± SD)
KYN/TRP0.0382 ± 0.01020.0369 ± 0.0121
KYNA/KYN0.0196 ± 0.00600.0188 ± 0.0085
AA/KYN0.0087 ± 0.00270.0092 ± 0.0048
3HK/KYN0.0093 ± 0.00390.0111 ± 0.0052*
3HAA/3HK0.4319 ± 0.23170.9026 ± 0.4619***
3HAA/AA0.499 ± 0.3851.0893 ± 0.614***
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P < 0.05; ***P < 0.001 vs. HCs