Pearson’s correlation coefficients (|r| > 0.3) between the TRP-KYN pathway metabolites and cytokine levels (A) and between PASI score and cytokine levels (B) in PSOs
| (A) | TRP-KYN pathway metabolites | Cytokines | Correlation coefficient |
|---|---|---|---|
| AA | IP-10 | 0.64 | |
| KYN | IP-10 | 0.49 | |
| AA | FLT3-L | 0.38 | |
| TRP | EGF | 0.37 | |
| KYN | MIG | 0.37 | |
| AA | MDC | 0.32 | |
| AA | MIG | 0.32 | |
| TRP | MIG | –0.32 | |
| AA | MIP-1β | 0.31 | |
| 3HK | IL-17F | –0.31 | |
| KYNA | IP-10 | 0.30 | |
| AA | Fractalkine | 0.30 | |
| KYN | FLT3-L | 0.30 | |
| (B) | PASI score | Cytokines | Correlation coefficient |
| PASI score | IL-1RA | 0.45 | |
| PASI score | IL-9 | –0.30 |