Genotypic results of IL-6 (-174G/C) polymorphism in the literature
| Genotype | Controls | HT patients | ||||
|---|---|---|---|---|---|---|
| IL-6 -174 G>C | GG | GC | CC | GG | GC | CC |
| Our study (West Algeria) | 166/211(78.67%) | 43/211(20.38%) | 02/211(0.95%) | 65/81(80.25%) | 16/81(19.75%) | 0 |
| Erdogan et al. [16] (Turkey) | 5/110(4.5%) | 86/110(78.2%) | 19/110(17.3%) | 27/110(24.5%*) | 51/110(46.4%*) | 32/110(29.1%*) |
| Baki et al. [17] (Turkey) | 126/231(54.6%) | 90/231(39%) | 15/231(6.5%) | 117/190(61.6%) | 63/190(33.2%) | 10/190(5.2%) |
| Durães et al. [18] (Portugal) | 319/735(43.4%) | 324/735(44.1%) | 92/735(12.5%) | 156/418(37.3%) | 189/418(45.2%) | 73/418(17.5%*) |
| Aberkan [19] (Blida, center of Algeria) | 26/35(74.29) | 8/35(22.86) | 1/35(2.86) | 21/27(80.77) | 1/27(3.70) | 5/27(18.52) |
* Results statistically significant (P value < 0.05). HT: Hashimoto’s thyroiditis; IL-6: interleukin-6