Exploration of Neuroprotective Therapy

Table 1

Examples of miRNAs biomarkers for various neurological disorders

S.No	Disease	Sample source	miRNA	Method	Reference
1.	AD	Plasma	miR-342-5p	qRT-PCR	[50]
2.	AD	Brain tissue	miR-31	qRT-PCR	[51]
3.	AD	Brain tissue	miR-132	qRT-PCR	[52]
4.	AD	Brain tissue	miR-212-5p	qRT-PCR	[53]
5.	AD	Cell line	miR-124	qRT-PCR	[54]
6.	AD	Brain tissue	miR-146a	qRT-PCR	[55]
7.	PD	Tissues	miR-34c	qRT-PCR	[56]
8.	PD	Brain tissue	miR-599	qRT-PCR	[57]
9.	PD	Tissue and cell line	miR-21	qRT-PCR	[58]
10.	PD	Brain tissue	miR-185	qRT-PCR	[59]
11.	PD	Cells	miR-34a	qRT-PCR	[60]
12.	PD	Serum	miR-218-5p, miR-320a-5p	qRT-PCR	[61]
13.	PD	Brain tissue	miR-543	qRT-PCR	[62]
14.	PD	Brain tissue	miR-10b-5p	Illumina sequencing	[63]
15.	PD	Brain tissue	miR-7	qRT-PCR	[64]
16.	PD	Plasma	miR-23b-3p	Illumina sequencing	[65]
17.	PD	Serum	miR-214	qRT-PCR	[66]
18.	PD	Plasma	miR-133b, miR-221-3p	qRT-PCR	[67]
19.	PD	Serum	miR-223-3p, miR-7-1-5p	qRT-PCR	[35]
20.	PD	Saliva	miR-29a-3p, miR-29c-3p	Microarray/qRT-PCR	[68]
21.	AD	Serum	miR-93	qRT-PCR, Solexa sequencing	[69]
22.	AD	Cell culture	miR-298	qRT-PCR	[70]
23.	AD	PBMC	miR-150-5p	qRT-PCR	[71]
24.	AD	Serum	miR-28-3p	qRT-PCR	[72]
25.	AD	Serum	miR-128	qRT-PCR	[73]
26.	AD	Serum	miR-455-3p	qRT-PCR	[74]
27.	AD	Brain tissue	miR-129-5p	qRT-PCR, Illumina sequencing	[75]
28.	AD	Serum	miR-331-3p	qRT-PCR	[76]
29.	AD	Plasma	miR-103, miR-107	qRT-PCR	[77]

PBMC: peripheral blood mononuclear cells