From:  Advances in pharmacogenomics: optimizing antiepileptic drug therapy for drug-resistant epilepsy

Genetic variants associated with ASM safety

Gene variantAssociated drugSevere adverse reactionsEthnic groupReference
HLA-B*1502Carbamazepine (CBZ)Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)Han-Chinese, Thai, and Malaysian[34]
HLA-A*3101Carbamazepine (CBZ)Hypersensitivity reactionsEuropean populations[35]
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