Exploration of Neuroscience

From: Therapeutic potential of extracellular vesicles in Parkinson’s disease

Table 1

Studies utilizing unmodified EVs on PD models

Therapeutic cargo	EV source	Experiment type	Ref.
Natural EV-cargo	SHEDs	In vitro	[74]
Natural EV-cargo	SHEDs	In vivo	[75]
Natural EV-cargo	hUC-MSCs	In vitro and in vivo	[71]
Natural EV-cargo but rich in miRNA-106b	hUC-MSCs	In vitro and in vivo	[70]
Natural EV-cargo but rich in Wnt5	BM-MSCs and BM-MSC-derived DA neuron	In vivo	[77]
Natural EV-cargo	BM-MSCs	In vivo	[79]
Natural EV-cargo but rich in Wnt5	BM-MSCs and BM-MSC-derived DA neuron	In vivo	[78]
Natural EV-cargo	hUC-MSCs	In vitro and in vivo	[76]

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