State | Stage | % of total sleep1 | Body and brain activity | Mechanism and benefits | |
---|---|---|---|---|---|
NREM | 1 | N1 | 2–5 | Low-voltage, mixed-frequency brain waves | Transitions from wakefulness and low arousal threshold |
2 | N2 | 45–55 | Low-voltage, low-frequency brain activity with spindles; reduces muscle tension | Associated with memory consolidation and learning | |
3 | N3 | 3–8 | Increased high-voltage SWS activity | Transition to stage 4; HGH release [41] | |
4 | 10–15 | Increased high-voltage, SWS; some body movements | HGH release [41] | ||
REM | 20–25 | Low-voltage, mixed-frequency brain activity; muscle atonia; bursts of REM; irregular HR and breathing (including short breathing apnea) | Dreaming, mood regulation, and antidepressant effects are most often associated with REM sleep; memory consolidation in REM is still debated |
HGH: human growth hormone; HR: heart rate; NREM: non-rapid eye movement; REM: rapid eye movement; SWS: slow-wave sleep; 1 Estimated for healthy young adults [38]