Exploration of Asthma & Allergy

Table 2.

Summary of disease control, spirometry and airway inflammation before and 1 year after the start of biologics at the Pediatric Asthma Center

Disease control and instrumental data	Case 1		Case 2		Case 3		Case 4
Disease control and instrumental data	Pre	Post	Pre	Post	Pre	Post	Pre	Post
C-ACT	8	23	16	20	13	20	10	22
Asthma attacks/year	8	2	12	6	9	2	10	3
FEV₁ (%pred)	61	82	85	90	89	111	67	75
FVC (%pred)	88	100	104	104	111	132	117	97
FEV₁/FVC (%)	69	81	81	86	80	84	57	77
FEF_25–75 (%pred)	71	96	66	80	73	89	25	82
FeNO (ppb)	38	14	53	14	120	42	24	17

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C-ACT: childhood asthma control test; FEV₁: forced expiratory volume during the first second; FVC: forced vital capacity; FEF_25–75: forced mid-expiratory flow; FeNO: fractional exhaled nitric oxide