Echocardiographic differences between the group with cardiotoxicity and the group without cardiotoxicity
| Variables | Patients with cardiotoxicity | Patients without cardiotoxicity | P |
|---|---|---|---|
| Diastolic diameter (mm) | 43.3 ± 5.7 | 42.6 ± 5 | 0.254 |
| Systolic diameter (mm) | 27.6 ± 6.3 | 27.0 ± 5.1 | 0.383 |
| Septum (mm) | 8.2 ± 2.1 | 8.4 ± 1.4 | 0.362 |
| Posterior wall (mm) | 8 ± 1.4 | 8.2 ± 1.4 | 0.275 |
| Left ventricular mass (g/m2) | 71.1 ± 15.7 | 66 ± 16.7 | 0.127 |
| RWT | 0.38 ± 0.11 | 0.38 ± 0.08 | 0.418 |
| LVEF (%) | 58.6 ± 10.6 | 63.7 ± 6 | 0.005 |
| GLS (%) | 13.9 ± 1.9 | 19.4 ± 4.2 | < 0.001 |
| Postsystolic contractions | 74.5% | 16.5% | < 0.001 |
| GWI (mmHg%) | 1,421.4 ± 396.7 | 1,925.4 ± 448 | < 0.001 |
| GCW (mmHg%) | 1,669.6 ± 399 | 2,115.1 ± 484 | < 0.001 |
| GWW (mmHg%) | 179.8 ± 106.7 | 135.3 ± 106 | 0.015 |
| GWE (%) | 88.2 ± 5 | 104.6 ± 138 | 0.246 |
| Mechanical dispersion (ms) | 76.7 ± 35 | 47.3 ± 15.9 | < 0.001 |
RWT: relative wall thickness; LVEF: left ventricular ejection fraction; GLS: global longitudinal strain; GWI: global myocardial work index; GCW: Global Constructive Work; GWW: Global Wasted Work; GWE: Global Work Efficiency