Molecular toolbox for nanomedicine
| Molecules | Immune responses | Genetic expression | Signaling pathways |
|---|---|---|---|
| Superparamagnetic iron oxide nanoparticle probes | Used in immune cell labeling and tracking | Can modulate genetic expression when functionalized with specific ligands | Can mimic natural signaling pathways when designed to target specific receptor |
| Nanoscale delivery systems | Can be engineered to modulate immune responses for targeted therapy | Have the potential to modulate genetic expression for therapeutic purpose | Can be designed to mimic natural signaling pathways for targeted drug delivery |
| Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system | Used for molecular detection in immune-related research | Can be employed to modulate genetic expression through gene editing | Utilized to study and manipulate natural signaling pathways within cells |
AVS, PB, and AKU equally contributed to: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. AP, JU, and JB: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. VT, DG, and MT: Validation, Writing—review & editing, Supervision. RM and PZ: Supervision, Project administration. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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The data supporting the findings of this study are available upon request.
This study was funded by the application of multivalent biomineralized nanostructures as a modular strategy for targeting colorectal cancer [CDIRCC-2024-468] by Qatar University. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2024.