Pathological situations where bile is available and its analysis could be helpful
Pathological situations |
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Benign or indeterminate biliary stenoses |
Primary sclerosing cholangitis (PSC) |
Chronic cholangitis at risk of developing cholangiocarcinoma (CCA) [repetitive chronic secondary cholangitis, immunoglobulin G4 (IgG4)-related cholangitis, etc.] |
Chronic pancreatitis with biliary strictures |
Pancreatic cysts with biliary strictures |
Pancreatic ductal adenocarcinoma (PDAC), CCA, bile duct carcinoma (BDC), hepatocellular carcinoma (HCC), and ampullary cancer presenting biliary strictures and/or obstructive jaundice |
Pancreatic surgery (pancreaticoduodenectomy or total pancreatectomy) |
Acute cholangitis or cholecystitis |
Patients with jaundice |
Pathologies associated with biliary microcrystals: idiopathic acute pancreatitis, recurrent acute pancreatitis, unexplained biliary pain, and post-cholecystectomy biliary pain |
Liver surgery: hepatectomy and transplantation |