Studies (n = 3) evaluating liver stiffness by SWE and HCC occurrence in patients with HCV
| Author & year | Region | SVR | Patients (n) | Mean age (years) | F-U months | HCC (n) | Prevalence (%) | Proposed cut-off (kPa) | AUROC | Sens (%) | Spec (%) | PPV | NPV | LR+ | LR– |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hamada et al., 2018 [43] | Japan | SVR | 196 | 62 | 26 | - | - | ≥ 11 | 0.933 | 75 | 95 | 0.273 | 0.989 | 1.5 | 0.6 |
| Gyotoku et al., 2022 [42] | Japan | SVR during FU | 229 | 65.6 | 32.6 ± 19.5 | 8 | 3.5 | - | 0.86041 | - | - | - | - | - | - |
| Kumada et al., 2022 [41] | Japan | No | 525 | 72 | 60 | 21 | 4 | > 11.7 | 0.826 | 78.6 | 82 | - | - | 4.3 | 0.26 |
SWE: shear wave elastography; SVR: sustained virological respons