Studies (n = 5) evaluating liver stiffness by MRE and HCC occurrence in patients with mixed etiology
| Author & year | Region | Etiology(%) | Patients (n) | Mean age (years) | F-U months | HCC (n) | Prevalence (%) | Proposed cut-off (kPa) | AUROC | Sens (%) | Spec (%) | PPV | NPV | LR+ | LR– |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anaparthy et al., 2011 [56] | USA | Viral 57NAFLD 33Others 10 | 90 | 64 ± 10(pts with HCC) | - | 30 | 33 | - | - | - | - | - | - | - | - |
| Motosugi et al., 2013 [57] | Japan | HCV 65Others 35 | 132 | 70.5 | - | 66 | 50 | - | - | - | - | - | - | - | - |
| Lee et al., 2018 [54] | Japan | HBV 65.9HCV 10.6Others 23.5 | 217 | 59.7 ± 12.0 | 45.0 ± 17.6 | 33 | 15 | ≥ 4.4 | - | - | - | - | - | - | - |
| Ichikawa et al., 2019 [55] | Japan | HCV 62HBV 22Others 16 | 161 | - | - | 47 | 29.2 | - | - | - | - | - | - | - | - |
| Higuchi et al., 2022 [58] | Japan-USA | HCV 51.2HBV 15.8Others 33 | 2,373 | 68 | 33.6 | 99 | 4 | - | - | - | - | - | - | - | - |
NAFLD: non-alcoholic fatty liver disease