From:  Mesenchymal stem cell and exosome-based therapy for liver diseases: can it overcome conventional therapeutic inconsistencies?

Exosomes derived from various cells have different functions

Source of exosomesAction on liver fibrosisReference (s)
Human umbilical cord MSCInhibition[238, 239]
Adipose tissue-derived MSCInhibition[241]
Bone marrow derived MSCInhibition[243, 246, 254]
Amnion-derived MSCInhibition[244]
Embryonic stem cell-derived MSCInhibition[245]
Human liver stem cellInhibition[247]
Human induced pluripotent stem cellInhibition[248]
HCV infected hepatocytePromotion[242]
CholangiocytesPromotion[249, 250]
Neighboring quiescent HSCInhibition[240, 251]
NK CellInhibition[252]
M1 macrophagePromotion[253]
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Adapted with permission from [230]. © 2023 The Authors