From:  Utility of dimethylsulfoxide to preserve synovial fluid samples for microcrystal detection and identification

Agreement in the identification of microcrystals (kappa index) compared with reference with and without DMSO for both observers (disagreement shown in bold and underlined)

ReferenceDMSO+ observer 1DMSO+ observer 2DMSOobserver 1Observer 2
NegativeMSUCPPNegativeMSUCPPNegativeMSUCPPNegativeMSUCPP
Negative12002111101000
MSU080080170510
CPP0010009406212

Agreement kappa: 1.00 for reference vs. DMSO+ observer 1; kappa: 0.845 for reference vs. DMSO+ observer 2; kappa: 0.691 for reference vs. DMSO− observer 2; kappa: 0.111 for reference vs. DMSO− observer 2