Estimated ORs of SCD* based on logistic regression models (age < 55)**
| CDAI | Unadjusted | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
| Remission | Ref | Ref | Ref | Ref | Ref | Ref | ||||||
| Low | 4.19 | 3.13–5.62 | 3.33 | 2.48–4.47 | 3.29 | 2.45–4.43 | 2.95 | 2.18–3.97 | 1.86 | 1.37–2.51 | 1.80 | 1.33–2.45 |
| Moderate | 8.77 | 6.59–11.68 | 5.80 | 4.33–7.75 | 5.59 | 4.17–7.48 | 4.79 | 3.56–6.43 | 2.56 | 1.90–3.45 | 2.45 | 1.81–3.32 |
| Severe | 10.40 | 7.74–13.97 | 6.03 | 4.46–8.15 | 5.76 | 4.25–7.81 | 4.76 | 3.50–6.48 | 2.21 | 1.62–3.02 | 2.11 | 1.54–2.90 |
* SCD determined with patient self-report of difficulty thinking and confusion; ** log(π/(1 – π)) = β0 + β1 × Agelt55 + β2 × LDA + β3 × moderate + β4 × severe + β5 × Agelt55 × LDA + β6 × Agelt55 × moderate + β7 × Agelt55 × severe, where π is the probability of SCD; Agelt55 is an indicator (0/1) of age < 55; and LDA, moderate, and severe are indicators (0/1) of CDAI levels (age > 55 and CDAI remission are reference groups)