Comparison of epidemiologic and clinical characteristics of PDB and PsA
| Characteristics | PsA | PDB |
|---|---|---|
| Age of onset, years | > 45 | > 50 |
| Gender | F = M | F = M |
| Familial history | Positive | Positive |
| Vascular calcification | Is present | Is present |
| Involvement of weight—bearing bony architecture | Lower extremity enthesitis (obesity) | Lower-extremities (long-bones) |
| Pelvis | Pelvis | |
| Axial spondylitis | Axial skeleton | |
| Bone ALP | ↑↑ | ↑↑ |
| CD association | Yes | Possibly |
| OCLs morphology | Hypermultinucleated | Hypermultinucleated |
| Oxidative stress | ↑ | ↑ |
| Tissue vascularity | ↑↑ | ↑↑ |
| Pattern of bone involvement | Asymmetric | Asymmetric |
| Skipping non-marginal- syndesmophytes | Not crossing bone boundaries | |
| Deep Koebner phenomenon | Confirmed | ? |
| Daily trauma-related sites | DIP joints Ray distribution Dominant-hand thumbnail Obesity | Skull |
| Environmental factors | Streptococcus/Drugs/Stress | Measles virus |
| Prevalence | Increased | Decreased |
F: female; M: male; ↑: elevated; ↑↑: significantly elevated; ?: undetermined