Selectivity index of biaryl hydroxy-triazoles and fluorene-triazoles compounds comparing cytotoxicity on tumor cell lines to non-tumor HEK-293 cell line
| Compound | Cell lines | |||
|---|---|---|---|---|
| HCT-116 | SNB-19 | MDA-MB-231 | MOLM-13 | |
| LSO258 | ND | ND | ND | > 2 |
| LSO272 | ND | ND | ND | 2.76 |
| LSO276 | ND | ND | ND | 1.71 |
| LSO278 | 0.88 | ND | 0.60 | 1.11 |
| LSO281 | 0.87 | ND | ND | 1.08 |
| Doxorubicin | ND | 1 | 4 | ND |
| 5-fluorouracil | 0.35 | ND | ND | ND |
| Azacitidine | ND | ND | ND | > 50 |
ND: not determined