Exploration of Drug Science

From: Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents

Table 1

Growth inhibition area of the compounds 4, 6, 8, and 11 at 10 mg/mL by the agar well diffusion method against Gram-positive, Gram-negative bacteria, and yeast strains

Compound	Zone of inhibition/mm
Compound	*S. aureus*	*S. epidermidis*	*M. smegmatis*	*P. aeruginosa*	*S. cerevisiae*	*C. albicans*
4	n.a.	7	n.a.	n.a.	7	n.a.
6	n.a.	n.a.	n.a.	n.a.	8	n.a.
8	6	n.a.	n.a.	n.a.	8	n.a.
11	15	12	n.a.	n.a.	9	n.a.
Positive control	VAN 26	VAN 27	RIF 48	NOR 33	NYS 31	NYS 29

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n.a.: not active; NOR: norfloxacin; NYS: nystatin; RIF: rifampicin