Effect of compounds on the growth of human cancer cells
| Compound | GI50 (µmol/L) | ||
|---|---|---|---|
| HCT116 | MCF-7 | A375 | |
| 4 | > 50 | > 50 | > 50 |
| 6 | > 50 | 35.5 ± 1.5 | 23.8 ± 1.9 |
| 8 | > 50 | > 50 | > 50 |
| 11 | 3.55 ± 0.15 | 11.5 ± 0.5 | 9.6 ± 1.1 |
| Etoposide | 0.71 ± 0.06 | 2.70 ± 0.1 | 0.85 ± 0.09 |
GI50 values were determined by SRB assay after 48 h treatment (growth obtained with the vehicle set as 100%). Data are mean ± standard error of the mean (SEM) of four to six independent experiments. Etoposide was used as a positive control