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From: Subacute toxicity of isoliquiritigenin-zein phosphatidylcholine nanoparticles on biochemical, hematological, and histopathological parameters in Sprague-Dawley rats

Table 1

The body weights and clinical observations of treated KM mice and SD rats were recorded for a period of 7 days

Groups			Body weight (g)				Death/treated individuals	Mortality latency	Clinical signs
Groups			Day 1	Day 2	Day 3	Day 4	Death/treated individuals	Mortality latency	Clinical signs
KM mice	Control	Male	16.20 ± 1.25	16.64 ± 1.13	17.14 ± 1.16	17.64 ± 1.06	0/5	None	None
	Control	Female	18.42 ± 1.75	18.90 ± 1.74	19.40 ± 1.64	19.92 ± 1.61	0/5	None	None
	160 mg/kg	Male	15.62 ± 1.15	16.16 ± 1.16	16.60 ± 1.11	17.24 ± 1.09	0/5	None	None
	160 mg/kg	Female	18.38 ± 0.84	18.08 ± 0.81	19.32 ± 0.87	19.86 ± 0.9	0/5	None	None
SD rats	Control	Male	107.06 ± 2.36	116.70 ± 2.02	126.14 ± 2.61	134.20 ± 2.53	0/5	None	None
	Control	Female	114.34 ± 2.08	123.68 ± 2.32	133.74 ± 2.08	141.84 ± 3.27	0/5	None	None
	160 mg/kg	Male	106.84 ± 0.91	116.44 ±1.66	127.18 ± 2.41	135.02 ± 1.05	0/5	None	None
	160 mg/kg	Female	116.20 ± 2.54	125.44 ± 3.24	134.80 ± 3.50	143.94 ± 2.30	0/5	None	None

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Values are expressed as mean ± standard deviation, n = 5. The Dunnett t-test was used to determine the significance of data variability between the treated and control groups. Statistical significance was considered at ^*P < 0.05