Calculated potential energy of interaction (ΔE) and free energy of hydration (ΔG) for the interaction of fluevirines with the tubulin dimer
| Compounds | ΔE (kcal/mol) | ΔG (kcal/mol) |
|---|---|---|
| Securinine | –44.60 | –17.10 |
| Norsecurinine | –44.20 | –17.10 |
| Fluevirine A | –73.90 | –20.90 |
| Fluevirine B | –49.30 | –20.90 |
| Fluevirine C | –52.20 | –14.90 |
| Fluevirine D | –47.70 | –16.85 |
| Fluevirine E | –56.85 | –24.50 |
| Fluevirine F | –50.20 | –12.90 |