From:
Decoding vascular aging: implications for atherosclerosis progression and clinical intervention
Histone deacetylases (HDACs) inhibitors
| Drug | Model and mechanisms | Structure | Author | Reference |
|---|---|---|---|---|
| TMP195 | HDAC9 inhibition (hyperlipidemic mice) |  | Asare et al. (2020) | [163] |
| RGFP966 | HDAC3 inhibition (ApoE-/- mice) |  | Chen et al. (2021) | [164] |
| MC1568 | HDAC9 inhibition (ex vivo genetic knockout HDAC9 endothelial cells) |  | Lecce et al. | [165] |
| Sodium valproate | HDAC9 inhibition (human patients) |  | Brookes et al. (2018) | [166] |