Epitopes identified in Latin American scorpion toxins
Venom animal | Toxin (UniProt) | Epitope peptide | Epitope mapping | Immunogen | Reference |
---|---|---|---|---|---|
Tityus serrulatus | Ts3 (P01496) | L50PDSEPTKTNGKCKS64 | Spot synthesis | Peptide bound to KLH | [36] |
Ts4 (O77463) | G1REGYPADSKGCKIT15, T29LKKGSSGYCAWPAC43, P49DSVKIWTSETNKCG63 | ||||
Tityus serrulatus | Ts1 (P15226) | K1EGYLMDHEGSKLSSAGC15, I17RPSGYSGRESGIKKAGC31, L47PNWVKVWDRATNKAGC61 | Spot synthesis | Peptide bound to KLH | [37] |
Ts2 (P68410) | K1EGYAMDHEGSKFSSAGC15, V48PDHIKVWDYATNKSAGC62 | ||||
Ts3 (P01496) | K1KDGYPVEYDNSAYIAGC15, W16NAYSDKLSKDKAGC30, G48LPDSEPTKTNGKSKAGC62 | ||||
Tityus serrulatus | Ts4 (O77463) | G1REGYPAD8-GG-G47LPDSVKI54 | Spot synthesis | Peptide bound to OVA | [38] |
Tityus trivittatus | Tt1g (P0DMM8) | LPNWVKVWERATNR-Abu | Informatic | Branched or palmitoylated peptide | [53] |
Abu: α-aminobutyric acid; KLH: keyhole limpet hemocyanin; OVA: ovalbumin