Modified residues or molecules to be used in synthesis for special requirements
| Amino acid | Structure | Use | References |
|---|---|---|---|
| Fmoc-Lys(Fmoc)-OH |  | Synthesis of peptide dimers using the side chain to grow a new peptide chain | [78] |
| Fmoc-Lys(Dde)-OH |  | Used when it is necessary to make bonds with the lysine side chain, for example in the case of branched peptides, template structured peptides, or for bonding with metal groups. | |
| J ligandMalonic or Propanodioic acid |  | Used to induce structured peptides in conjunction with Lys(Dde) | |
| Fmoc-DOPA-OH |  | Catecholic amino acid related to adhesive properties of mussel foot proteins | [70] |
| Deuterated Fmoc-Lys(Boc)-OH |  | Track of peptide by nuclear magnetic resonance (NMR) | [79] |
Compounds structures were drawn with ACD/Chemsketch 2021.2.1 [77]. Fmoc: fluorenylmethyloxycarbonyl; Dde: [1-(4,4-dimethyl-2,6-dioxycyclohex-1-ylidine)ethyl]; DOPA: L-3,4-dihydroxyphenylalanine; Boc: tert-butoxycarbonyl