Exploration of Drug Science

Table 1

Antimicrobial drugs with their mechanism of action

S. No.	Antimicrobial drugs	Use	Target microbe	References
1	Antisense phosphorothioate oligonucleotide	Helps fluoroquinolone-resistant Escherichia coli regain antibiotic sensitivity by targeting acrB gene	Escherichia coli	[14]
2	Amikacin	Effective against bacterial infections	Mycobacterium and Pseudomonas aeruginosa	[15]
3	Vancomycin and linezolid	Used to treat complex skin and soft-tissue infections brought on by methicillin-resistant Staphylococcus aureus (MRSA) as well as nosocomial pneumonia	Staphylococcus aureus	[16]
4	Penicillin G procaine and pirlimycin	Used for treating mastitis in lactating cows	Mycoplasma spp. and Streptococcus agalactiae	[17]
5	Silica-based biomaterials loaded with ferulic acid	Used in bone tissue engineering to promote bone graft healing and stop bacterial infections	Staphylococcus aureus and E. coli	[18]
6	Non-canonical amino acids (NCAAs)	Plays a role in designing antimicrobial peptides to combat multidrug-resistant bacteria	Gram-positive and Gram-negative bacteria	[19]
7	Ciprofloxacin	This medication is a component of a new thermo-responsive hydrogel formulation intended for drug-eluting uses	Gram-negative bacteria	[20]
8	Taromycin A and Gassericin A	Exhibit binding mechanism by interacting with Lys 234	Antibiotic resistant bacteria that produce TEM-1 β-lactamases	[21]