From:  Combating antibiotic resistance: mechanisms, challenges, and innovative approaches in antibacterial drug development

Broad spectrum antibacterials with their binding site function

Broad spectrum antibacterialBinding site functionReferences
QuinolonesInhibit DNA replication by binding to DNA gyrase and topoisomerase IV.[43]
CarbapenemsInhibit cell wall synthesis by binding to penicillin-binding proteins.[49]