Cytotoxic effect of the dimeric peptides against DU-145, HeLa, and HT-29 cell lines (2 h)
Code | Sequence | IC50 (µM) | ||
---|---|---|---|---|
HT-29 | DU-145 | HeLa | ||
26[F] | (RRWQWRFKKLG)2-K-Ahx | 12 | 17 | 7 |
3 | (R-Orn-WQWRFKKLG)2-K-Ahx | 30 | 29 | 29 |
4 | (RRWQW-Orn-FKKLG)2-K-Ahx | 49 | > 62 | > 62 |
8 | (Biotin-Ahx-RRWQWRFKKLG)2-K-Ahx | 17 | 29 | 14 |