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From: Controlled release of dexamethasone phosphate from modified mesoporous biocompatible silica nanoparticles: synthesis, characterization, and kinetic studies

Table 2

Kinetic parameters and results for DexaP desorption models from MSN

Model	Parameter	4°C	25°C	37°C
Zero order	k₀ (mg h^–1)	0.45 ± 0.05	0.63 ± 0.06	0.85 ± 0.08
First order	k₁ (h^–1)	0.22 ± 0.02	0.30 ± 0.03	0.41 ± 0.04
Higuchi	k_H (mg h^–1/2)	2.45 ± 0.20	3.12 ± 0.25	4.01 ± 0.30
Korsmeyer-Peppas	n	0.46 ± 0.02	0.54 ± 0.03	0.68 ± 0.04

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DexaP: dexamethasone phosphate; MSN: mesoporous silica nanoparticle; k₀: zero-order related constant; k₁: first-order release constant; k_H: Higuchi constant; n: diffusional exponent