Contents
Special Issue Topic

Cardiovascular Risk for Mothers and Offspring Resulting from Complicated Pregnancy

Submission Deadline: June 30, 2025

Guest Editor

Ilona Hromadnikova E-Mail

Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, Prague, Czech Republic

Research Keywords: pregnancy-related complications – pathogenesis, diagnosis, prediction, prevention, short-term and long-term cardiovascular risk for mothers and offspring

About the Special lssue

Pregnancy-related complications such as gestational hypertension (GH), preeclampsia (PE), HELLP (Hemolysis, Elevated Liver enzymes and Low Platelets) syndrome, fetal growth restriction (FGR), small for gestational age (SGA), gestational diabetes mellitus (GDM), preterm birth (spontaneous preterm birth or preterm premature rupture of membranes), and pregnancy loss (late miscarriage and stillbirth) induce long-term metabolic and vascular abnormalities that might increase the overall risk of metabolic, cardiovascular, cerebrovascular, kidney, and other diseases later in life in mothers and their offspring.

This special issue aims to provide an overview of the latest research on the mechanisms, diagnostic and/or prognostic modalities, and treatment strategies associated with pregnancy-related complications leading to the consequent development of metabolic and cardiovascular abnormalities (hypertension, dyslipidaemia, hyperglycaemia, obesity, echocardiography (ECHO) and electrocardiogram (ECG) abnormalities, endothelial dysfunction, etc.) and to the consequent onset of metabolic, cardiovascular, and cerebrovascular diseases (diabetes mellitus, myocardial infarction, cerebral infarction, systolic or diastolic heart failure, pulmonary arterial hypertension, etc.).

This comprehensive special issue will be of interest not only to scientists but also to physicians from different complementary disciplines such as gynecology and obstetrics, cardiology, preventive medicine, general medicine, neonatology, and paediatrics. Just the interconnection of various expertises may bring benefits to our patients and significantly improve the physical health of a broader population.

Keywords: Gestational hypertension, preeclampsia, HELLP syndrome, fetal growth restriction, gestational diabetes mellitus, preterm birth, pregnancy loss, cardiovascular risk, cardiovascular disease, cerebrovascular disease

Published Articles

Open Access Case Report
Implications of mechanical circulatory support devices in a pregnant woman with cardiogenic shock
Data on the use of mechanical circulatory support devices in pregnant women are limited. A 27-year-old woman at 27 weeks and 6 days of gestation was supported by three different mechanical circulato
Published: January 13, 2025 Explor Cardiol. 2025;3:101244
664 40 0
Open Access Review
Epigenetic mechanisms linking pregnancy complications to cardiovascular disease in offspring
Pregnancy complications such as pre-eclampsia, gestational diabetes, and intrauterine growth restriction (IUGR) not only present immediate risks to maternal and fetal health but also have long-term
Published: November 07, 2024 Explor Cardiol. 2024;2:241–252
1536 139 0