Exploration of Medicine

From: Treatment opportunities with Fernandoa adenophylla and recent novel approaches for natural medicinal phytochemicals as a drug delivery system

Table 1

FA plant parts pharmacological activity

Serial number	Plant part	Plant extract used	Experimental model	Outcome	Reference number
1	Leaves	Aqueous extract	Earthworm	Analgesic, antipyretic and anti helminthic	[22–24]
2	Bark	Hexane, ethyl acetate extract/methane extract (by percolation method)	Culture media of Bacillus cereus, S. aureus, Pseudomonas aeroginosa, Salmonella typhi, Shigella Boydii and E. coli	Antibacterial and anti-oxidant	[25–31]
3	Root	Dichloro methane extract (using Soxhlet apparatus)	Culture media of Trichophyton mentagophyte, Microsporum gypsum, Epidermophyton floccosum, Penicillum expansum, and Aspergillus niger	Anti fungal	[31–35]
4	Leaves and seeds	Methanolic extract (by cold maceration process)	Culture media of S. aureus, E. coli, Pseudomonas aeroginosa, Bacillus subtilis and Staphylococcus epidermidis (S. epidermidis)	Anti microbial	[36–39]
5	Root (heartwood)	Methanolic extract (by cold extraction process)	BALB/c mice of both sexes	Antinociceptive, muscle relaxant, and sedative	[1, 40–42]
6	Root (heartwood)	Methanolic extract (using Soxhlet apparatus)	In silico docking study	Potent urease inhibitor	[43–46]
7	Leaves	Maceration process	Culture media of Pseudomonas aeroginosa, Klebsiella pneumonia, Citrobacter, E. coli, Enterobacter, Acinetobacter, Providencia, and methicillin-resistant S. aureus	Antibacterial (UTI)	[25–31]
8	Leaves	Methanolic extract (by using hot percolation method)	By formulation of culture media of Klebsiella pneumonia, Bacillus anthracis, Salmonella enterica, S. aureus, and E. coli	Anti microbial	[30, 36–39]
9	Stem	Cold extraction	BALB/c mice of both sexes	Anti-inflammatory effects	[47–51]

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E. coli: Escherichia coli; S. aureus: Staphylococcus aureus; UTI: urinary tract infections