FMEA matrix to identify the criticality of failure modes on the basis of RPN scores
| S. No. | Failure modes | Severity (S) | Occurrence (O) | Detection (D) | RPN (S × O × D) | Risk |
|---|---|---|---|---|---|---|
| 1 | Stirring speed (rpm) | 4 | 3 | 2 | 24 | Medium |
| 2 | Stirring time (min) | 4 | 4 | 2 | 32 | Medium |
| 3 | SA (%) | 4 | 5 | 2 | 40 | Medium |
| 4 | ST (min) | 5 | 5 | 2 | 50 | High |
| 5 | Total lipid conc. (%) | 5 | 5 | 3 | 75 | High |
| 6 | Surfactant conc. (%) | 5 | 5 | 3 | 75 | High |
| 7 | Rate of mixing | 2 | 1 | 2 | 4 | Low |
| 8 | Temperature (°C) | 3 | 3 | 2 | 18 | Medium |
| 9 | Bead size | 2 | 2 | 1 | 4 | Low |
| 10 | Bead shape | 1 | 1 | 1 | 1 | Low |
| 11 | Beaker size | 2 | 2 | 1 | 4 | Low |
| 12 | Beaker color | 1 | 1 | 1 | 1 | Low |
conc.: concentration; rpm: rotation per minute; SA: sonication amplitude; ST: sonication time