A summary of the functions of autophagy-related circRNAs
| circRNAs | Expression | Regulation targets and pathways | Influence on autophagy | Diseases | Refs |
|---|---|---|---|---|---|
| circCDYL | Up | circCDYL/miR-1275/ATG7/ULK1 axis | Enhancement | Breast cancer | [76] |
| circCUL2 | Down | circCUL2/miR-142-3p/ROCK2 axis | Enhancement | Gastric cancer | [80] |
| circHIPK3 | Down | circHIPK3/miR-124-3p/STAT3/PRKAA axis | Enhancement | Lung cancer | [81] |
| circHECTD1 | Up | circHECTD1/miR-142/TIPARP axis | Enhancement | Cerebral ischemic stroke | [46] |
| circSHOC2 | Up | circSHOC2/miR-7670-3p/SIRT1 axis | Suppression | Cerebral ischemic stroke | [75] |
| circ_002581 | Up | circ_002581/miR-122/CPEB1 axis | Suppression | Nonalcoholic steatohepatitis | [82] |
circCDYL: circular RNA CDYL; ULK1: UNC-51-like kinase 1; circCUL2: circular RNA CUL2; ROCK2: rho-associated coiled-coil-containing protein kinase-2; circHIPK3: circular RNA HIPK3; STAT3: signal transducer and activator of transcription 3; PRKAA: protein kinase AMP-activated catalytic subunit alpha 2; TIPARP: TCDD inducible poly[ADP-ribose] polymerase; circSHOC2: circular RNA SHOC2; SIRT1: sirtuin 1; CPEB1: cytoplasmic polyadenylation element-binding 1