From:  The role of microbiome in uveitis

Characterization of gut dysbiosis in different autoimmune conditions compared to healthy or disease controls

DiseaseAuthorStudy objectStudy findings
Increased microbiotaDecreased microbiota
BDYasar et al., 2020 [40]27 BD vs. 10 HCsLachnospiraceae NK4A136, Actinomyces, Libanicoccus, Collinsella, Eggerthella, Enetrohabdus, Catenibacterium, EnterobacterBacteroides, Cricetibacter, Alistipes, Lachnospira, Dielma, Akkermansia, Sutterella, Anaerofilum, Ruminococcease-UCG007, Acetanaerobacterium, Copropaacter
Shimizu et al., 2019 [41]13 BD vs. 27 HCsEggerthella lenta, Acidaminococcus bifidum, Lactobacillus iners, Streptococcus species, Lactobacillus salivariusMegamonas hypermegale, Butyrivibrio, Streptococcus infantis, Filifacto
Oezguen et al., 2019 [42]13 BD vs. 14 HCsParabacteroides, Clostridiales, Geminger, Butyricimonas, Actinobacteria, ErysipelotrichaceaeVampirovibrio, unclassified Lachnospiraceae, Prevotella
Ye et al., 2018 [33]32 BD vs. 74 HCsBilophila spp., Parabacteroides spp., Paraprevotella spp., Stenotrophomonas spp., Actinomyces spp., Corynebacterium spp.Clostridium spp. (BPB), Methanoculleus spp., Methanomethylophilus spp.
VKHYe et al., 2020 [39]55 VKH vs. 52 HCsRamularia, Alternaria, RhizophagusMethanoculleus, Candidatus Methanomethylophilus, Azospirillum
Li et al., 2022 [43]11 VKH vs. 11 HCs vs. 20 NIASStomatobaculum, Pseudomonas, LachnoanaerobaculumGordonibacter, Slackia
ASZhang et al., 2020 [44]20 AS vs. 19 HCsPrevotellaceae, Actinomycetaceae, Dialister, Escherichia-Shigella, KlebsiellaLachnospiraceae, Bacteroides, Parasutterella, Bifidobacterium
Yin et al., 2020 [45]127 AS vs. 123 HCsClostridiales bacterium 1_7_47FAA, Clostridium hatheway, Clostridium bolteaeBifidobacterium adolescentis, Coprococcus comes, Lachnospiraceae bacterium 5_1_63FAA, Roseburia inulinivorans
Klingberg et al., 2019 [46]150 AS vs. 17 HCsProteobacteria, Enterobacteriaceae, Bacilli, Streptococcus species, ActinobacteriaBacteroides, Lachnospiraceae
IBDTakahashi et al., 2016 [47]10 IBD vs. 10 HCsActinomyces, BifidobacteriumBacteroides, Eubacterium, Faecalibacterium, Ruminococcus
Franzosa et al., 2019 [48]121 IBD vs. 34 HCsBifidobacterium breve, Clostridium symbiosum, Ruminococcus gnavusa, Escherichia coli, Clostridium clostridioformeRoseburia hominis, Dorea formicigenerans, Ruminococcus obeum
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HCs: healthy controls; AS: ankylosing spondylitis; NIAS: non-infectious anterior scleritis