Testing genetic association of TGFBR2 (rs764522) gene polymorphism with CHD (n = 175, adjusted by sex)
| Genotypic states | Genotype | Cases | Controls | OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Codominant | C/C | 14 (18.7%) | 40 (40.0%) | 1.00 | < 0.0001* |
| C/G | 45 (60%) | 60 (60%) | 0.43 (0.20–0.90) | ||
| G/G | 16 (21.3%) | 0 (0.0%) | 0.00 (0.00–NA) | ||
| Dominant | C/C | 14 (18.7%) | 40 (40.0%) | 1.00 | 0.001* |
| C/G + G/G | 61 (81.3%) | 60 (60.0%) | 0.31 (0.15–0.65) | ||
| Recessive | C/C + C/G | 59 (78.7%) | 100 (100.0%) | 1.00 | < 0.0001* |
| G/G | 16 (21.3%) | 0 (0.0%) | 0.00 (0.00–NA) | ||
| Overdominant | C/C + G/G | 30 (40%) | 40 (40%) | 1.00 | 0.86 |
| C/G | 45 (60%) | 60 (60%) | 0.94 (0.51–1.76) |
NA: not applicable; *: P-value significant < 0.05