Testing genetic association of TGFBR2 (rs6785358) gene polymorphism with CHD (n = 175, adjusted by sex)
| Genotypic states | Genotype | Cases | Controls | OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Codominant | A/A | 31 (41.3%) | 46 (46.0%) | 1.00 | 0.0073* |
| A/G | 30 (40%) | 50 (50%) | 1.13 (0.59–2.14) | ||
| G/G | 14 (18.7%) | 4 (4.0%) | 0.20 (0.06–0.66) | ||
| Dominant | A/A | 31 (41.3%) | 46 (46.0%) | 1.00 | 0.56 |
| A/G + G/G | 44 (58.7%) | 54 (54.0%) | 0.83 (0.46–1.53) | ||
| Recessive | A/A + A/G | 61 (81.3%) | 96 (96.0%) | 1.00 | 0.0018* |
| G/G | 14 (18.7%) | 4 (4.0%) | 0.19 (0.06–0.60) | ||
| Overdominant | A/A + G/G | 45 (60%) | 50 (50%) | 1.00 | 0.19 |
| A/G | 30 (40%) | 50 (50%) | 1.49 (0.81–2.74) |
*: P-value significant < 0.05