From:  Can magnetic nanoparticles enhance adoptive cell therapy via driving migration of lymphocytes into tumors?

Comparison of experiment designs in the studies by Sanz-Ortega L et al. [38] and Nie W et al. [42]

Experiment parameterSanz-Ortega L et al. [38]Nie W et al. [42]
MNP typesSingle MNPs MNCs built from 10 nm units
Size of MNPs13 nmUp to 100 nm
MNP-coatingAPTESPEI
EMF exposure time90 minutes24 hours
Method of OVA-peptide-specific CTL-activationConventional APCsBiomimetic aAPC
Return to article view

aAPC: artificial antigen-presenting cell; APTES: 3-aminopropyl-triethoxysilane; CTL: cytotoxic T-lymphocyte; EMF: external magnetic field; MNCs: magnetic nanoclusters; MNP: magnetic nanoparticle; OVA: ovalbumin; PEI: poly(ethylenimine)