PIPER results of dimerized cancer HER2/ERBB2 structure (PDB ID 3WLW) showing stable dimer values (using Schrödinger Release 2023-4: BioLuminate, Schrödinger, LLC, New York, NY, 2023)
| Title | PIPER pose energy | PIPER pose score | PIPER model number | PIPER cluster size |
|---|---|---|---|---|
| POSE1 | –1,238.94 | –192.131 | 50 | 93 |
| POSE2 | –1,099.976 | –481.194 | 251 | 90 |
| POSE3 | –1,075.053 | 90.941 | 341 | 77 |
| POSE4 | –1,234.521 | 288.706 | 53 | 51 |
| POSE5 | –967.27 | –65.814 | 969 | 50 |
| POSE6 | –1,162.564 | –34.34 | 139 | 45 |
| POSE7 | –1,132.691 | –130.897 | 187 | 40 |
| POSE8 | –965.985 | –119.112 | 984 | 35 |
| POSE9 | –1,156.086 | 307.185 | 141 | 33 |
| POSE10 | –1,212.369 | –80.513 | 73 | 32 |
| POSE11 | –1,083.691 | –10.777 | 297 | 32 |
| POSE12 | –974.888 | 43.566 | 899 | 32 |
| POSE13 | –1,006.026 | –18.822 | 683 | 31 |
| POSE14 | –1,041.641 | 142.197 | 479 | 29 |
| POSE15 | –1,041.1 | 61.322 | 483 | 24 |