Perspective classes, characteristic genes, and defining traits of AD patients
| Perspective class | Number of subjects | Gene name | Gene symbol | Defining trait |
|---|---|---|---|---|
| I | 156 | Tubulin beta 1 class VI | TUBB1 | Vasculogenesis |
| Ankyrin repeat and SOCS box-containing protein 4 | ASB4 | |||
| Phosphodiesterase 5A | PDE5A | |||
| II | 164 | Neuregulin-2 | NRG2 | Cell signaling and differentiation |
| Zinc-finger 3 | ZNF3 | |||
| III | 84 | Insulin-like growth factor 1 | IGF1 | Metabolism |
| Ankyrin repeat and SOCS box-containing protein 4 | ASB4 | |||
| G2 and S-phase expressed protein 1 | GTSE1 | |||
| IV | 134 | cDNA FLJ39269 | Nitric oxide | |
| Integrin subunit alpha | ITGA1 | |||
| Carboxypeptidase M | CPM | |||
| V | 76 | Phosphodiesterase 5A | PDE5A | Mitochondrial |
| Presenilin 1 | PSEN1 | |||
| NADH-coenzyme Q reductase | NDUFS8 | |||
| VI | 228 | DDB1 and CUL4 associated factor 17 | DCAF17 | Metal ion transport |
| cDNA FLJ75819 | ||||
| Solute carrier family 33 member 1 | SLC33AI |
SOCS: suppressor of cytokine signaling; NADH: nicotinamide adenine dinucleotide; DDB1: DNA damage-binding protein 1; CUL4: cullin-4