Exploration of Medicine

Table 3

Inter- and intra-group comparisons, mean and standard deviation values of modified Xerostomia Quality of Life Scale (XeQoLS) questionnaire part 1 [8]

Domain	Question	Interval	Quality of life score (Mean ± SD)		p-value
Domain	Question	Interval	Group A	Group B	p-value
1. Physical functioning	1.1 Do you have difficulty chewing because of your dry mouth?	Baseline	61.30 ± 25.28	57.71 ± 27.35	0.416^ns
		After 2 weeks	32.17 ± 25.58	31.25 ± 25.25	0.885^ns
		p-value	< 0.001*	< 0.001*	-
	1.2 Do you have difficulty swallowing because of your dry mouth?	Baseline	51.30 ± 41.26	53.75 ± 42.00	0.307^ns
		After 2 weeks	40.43 ± 39.02	39.17 ± 39.00	0.809^ns
		p-value	0.006*	0.006*	-
	1.3 Is speech difficult because of your dry mouth?	Baseline	56.09 ± 30.41	55.00 ± 31.76	0.307^ns
		After 2 weeks	29.78 ± 27.16	30.62 ± 28.14	0.487^ns
		p-value	< 0.001*	< 0.001*	-
	1.4 Is taste affected by your dry mouth?	Baseline	30.00 ± 30.90	28.75 ± 30.83	0.999^ns
		After 2 weeks	23.48 ± 29.79	20.00 ± 27.50	0.266^ns
		p-value	0.012*	0.013*	-
2. Pain/discomfort	2.1 How dry is your mouth?	Baseline	72.61 ± 24.16	70.83 ± 27.81	0.589^ns
		After 2 weeks	29.13 ± 20.43	29.58 ± 19.89	0.784^ns
		p-value	< 0.001*	< 0.001*	-
	2.2 Do you have a burning sensation in your mouth?	Baseline	29.13 ± 30.88	29.58 ± 29.85	0.445^ns
		After 2 weeks	14.35 ± 20.41	13.75 ± 20.18	0.328^ns
		p-value	0.002*	0.002*	-
3. Other clinical acceptances	3.1 Do you have difficulty with sleeping caused by your dry mouth?	Baseline	57.83 ± 25.40	52.50 ± 23.08	0.233^ns
		After 2 weeks	25.87 ± 20.92	22.92 ± 22.93	0.501^ns
		p-value	< 0.001*	< 0.001*	-
	3.2 How often do you sip liquids for oral comfort when not eating?	Baseline	59.78 ± 22.59	56.88 ± 24.58	0.607^ns
		After 2 weeks	31.74 ± 20.54	26.88 ± 21.46	0.208^ns
		p-value	< 0.001*	< 0.001*	-

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* significant (p < 0.05). ns: non-significant (p > 0.05); SD: standard deviation. -: no data