Interaction effects between neuronal functionalities and sexa
| Group | Associated to | Ratio 1 | Ratio 2 | Functions |
|---|---|---|---|---|
| 1 | Female | >> 1 | >> 1 | Neurogenesis, generation of neurons, inorganic ion transport, cell metal ion homeostasis, response to corticosteroids |
| 2 | Female, but enhanced in Younger | >> 1 | > 1 | Cognition, learning/memory, cation ion homeostasis, metal ion transport |
| 3 | Female, but enhanced in MCI | > 1 | >> 1 | SNC process, neuron projection morphogenesis, morphogenesis in neuron differentiation |
| 4 | Female, but only in Younger | >> 1 | ≈ 1 | Behavior, modulation of chemical synaptic transmission, inorganic cation transport |
| 5 | Female, but only in MCI | ≈ 1 | >> 1 | Neuron development, neuron differentiation, cell projection morphogenesis, collateral sprouting, glial differentiation, neuron migration, axonogenesis, apoptosis, BDNF receptor signaling, glutamate secretion |
| 6 | Female in Younger, but Male in MCI | >> 1 | << 1 | Cell-cell signaling, trans-synaptic signaling, chemical synaptic transmission |
| 7 | Female, but only in Younger | >> 1 | NSb | Circulatory system, memory, associative learning, LT-memory, pain perception, NPC proliferation, gliogenesis, glial cell fate commitment, apoptosis, action potential, aging, axon guidance and ensheathment, IGFR1 signaling, response to hypoxia, inflammatory response, Ca2+ ion homeostasis |
| 8 | Male | << 1 | << 1 | Glutamatergic synaptic transmission |
| 9 | Male, but only in Younger | << 1 | NSb | Response to iron (Fe2+), copper ion (Cu2+) transport, negative regulation of neuron projections |
a The type of conditional association was determined by comparing the values of Ratio 1 and Ratio 2, which summarized the information from two factorials based on