Association between patient demographic and behavioral parameters with VDR genotypes
| SNPs | N | BsmI | ApaI | TaqI | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BB N = 16 | Bb N = 38 | bb N = 46 | AA N = 42 | Aa N = 44 | aa N = 14 | TT N = 41 | Tt N = 45 | tt N = 14 | ||||
| Age at diagnosis | < 60 years | 15 | 2 (13.3%) | 6 (40%) | 7 (46.7%) | 8 (53.3%) | 6 (40%) | 1 (6.7%) | 8 (53.3%) | 4 (26.7%) | 3 (20%) | |
| ≥ 60 years | 85 | 14 (16.5%) | 32 (37.6%) | 39 (45.9%) | 34 (40%) | 38 (44.78%) | 13 (15.3%) | 33 (38.8%) | 41 (48.2%) | 11 (12.9%) | ||
| p-value | 0.952 | 0.527 | 0.297 | |||||||||
| Smoking | Smoker | 55 | 10 (18.2%) | 22 (40%) | 23 (41.8%) | 18 (32.7%) | 31 (56.4%) | 6 (10.9%) | 23 (41.8%) | 23 (41.8%) | 9 (16.4%) | |
| Non-smoker | 45 | 6 (13.3%) | 16 (35.6%) | 23 (51.1%) | 24 (53.3%) | 13 (28.9%) | 8 (17.8%) | 18 (40%) | 22 (48.9%) | 5 (11.1%) | ||
| p-value | 0.620 | 0.023* | 0.676 | |||||||||
| Alcohol consumption | Alcoholic | 32 | 4 (12.5%) | 16 (50%) | 12 (37.5%) | 14 (33.3%) | 13 (29.5%) | 5 (35.7%) | 12 (37.5%) | 17 (53.1%) | 3 (9.4%) | |
| Non-alcoholic | 68 | 12 (17.6%) | 22 (32.4%) | 34 (50%) | 28 (66.7%) | 31 (70.5%) | 9 (64.3%) | 29 (42.6%) | 28 (41.2%) | 11 (16.2%) | ||
| p-value | 0.237 | 0.885 | 0.461 | |||||||||
SNPs: single nucleotide polymorphisms; * statistically significant