From:  Inflammatory mediators in nasal secretion in patients with bronchial asthma and allergic rhinitis with or without polyposis and hypertrophic sinonasal mucosa

Regression analysis of prognostic factors for polyposis and hypertrophic changes of sinonasal mucosa in children and adolescents with asthma and allergic rhinitis

DataAUC95% CISensitivity (%)Specificity (%)OR [95% CI]P-value
ECP0.7150.715 ± 0.05578.048.01.008 [1.002–1.013]< 0.001
IL-40.6740.674 ± 0.05774.446.01.005 [1.001–1.008]0.004
IL-10.6380.638 ± 0.05876.746.01.003 [1.000–1.006]0.023
VEGF0.5410.541 ± 0.06271.424.00.840 [0.332–0.939]0.500
IgЕ0.4630.463 ± 0.06269.022.00.694 [0.193–0.840]0.538

AUC: area under the curve; OR: odds ratio; ECP: eosinophil cationic protein; IL-4: interleukin 4; IgE: immunoglobulin E; VEGF: vascular endothelial growth factor