From:  Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Top associations for time to CD

ChrBPrsIDA1A2GeneGroupYale-PennCOGAYale-Penn + COGA
MAFAA PEA PAA + EA PAA PEA PHRPDirection
1166038842rs61835088TCFAM78BAll0.145.19
E-08		2.55
E-02		2.96
E-08		0.890.010.873.71
E-09		--------
5170894319rs112894747CGFGF18-LOC105377721AA0.039.01
E-06		NA9.01
E-06		0.01NA1.414.76
E-07		+-++
790978616rs74426341CGLOC105375392All0.041.46
E-06		5.70
E-07		1.46
E-06		0.080.621.372.52
E-07		?+-
+++++
790983464rs73404786AGLOC105375392EA0.042.75
E-01		5.20
E-08		4.19
E-07		0.080.741.382.37
E-07		++++
7121807926rs73721103TGAASSLOC102724527AA0.056.57
E-01		NA2.76
E-03		0.11NA1.304.00
E-07		++++
2120404237rs2825295TGAL157359.3-AP000431.1AA0.351.45
E-07		3.15
E-02		1.04
E-07		0.070.831.142.57
E-08		++++
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The order of the symbols corresponds to Yale-Penn 1, Yale Penn 2, Yale-Penn 3, COGA. If AAs and EAs are combined, the AA symbol precedes the EA symbol. A1: effect allele; A2: non-effect allele; MAF: minor allele frequency in the subset of the Yale-Penn cohort indicated in the Group column; P: P-value; Direction: effect direction of A1