Nanoparticle physicochemical properties influence pharmacokinetic and biological parameters
| Shape | Size | Surface | Material |
|---|---|---|---|
| Functionalization | Toxicity | Toxicity | Toxicity |
| Toxicity | Biodistribution | Biodistribution | Biodistribution |
| Stability | Opsonization | Stability | Opsonization |
| Biodistribution | Cellular uptake | Opsonization | Cellular uptake |
| Opsonization | Clearance | Tissue retention | Drug release |
| Cellular uptake | EPR effect | Clearance | |
| Tissue retention | Tissue retention | Tissue retention |